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A sparse array offers a significant reduction in the complexity of ultrasonic imaging systems by decreasing the number of active elements and associated electrical circuits needed to form a focused beam. Consequently, for 1-D arrays, it has been adopted in the development of miniaturized systems such as portable, handheld, or smartphone-based systems. Previously, we developed an analytic method […]

Piezoelectric films including coatings are widely employed in various electromechanical devices. Precise measurement for piezoelectric film properties is crucial for both piezoelectric material development and design of the piezoelectric devices. However, substrate constraint on the deformation of piezoelectric films could cause significant impacts on the reliability and accuracy of the […]

Time-of-flight diffraction (ToFD) is a widely used ultrasonic nondestructive evaluation (NDE) method for locating and characterizing rough defects, with high accuracy in sizing smooth cracks. However, naturally grown defects often have irregular surfaces, complicating the received tip diffraction waves and affecting the accuracy of defect characterization. This article proposes a self-attention […]

Acoustic tweezers have attracted attention in various fields of cell biology, including in vitro single-cell and intercellular mechanics. Compared with other tweezing technologies such as optical and magnetic tweezers, acoustic tweezers possess stronger forces and are safer for use in biological systems. However, due to the limited spatial resolution or limited size of target objects, acoustic […]

Transcranial ultrasound stimulation (TUS) holds promise for noninvasive neural modulation in treating neurological disorders. Most clinically relevant targets are deep within the brain (near or at its geometric center), surrounded by other sensitive regions that need to be spared clinical intervention. However, in TUS, increasing frequency with the goal of improving spatial resolution reduces the […]

Lung ultrasound (LUS) is an important imaging modality to assess the state of the lung surface. However, current LUS approaches are based on subjective interpretation of imaging artifacts, which results in poor specificity as quantitative evaluation lacks. The latter could be improved by adopting LUS spectroscopy of vertical artifacts. Indeed, parameterizing these artifacts with native frequency, […]

In this work, we investigate, for the first time, a low phase noise and wide tuning range voltage-controlled surface acoustic wave oscillator (VCSO) based on a lithium niobate on sapphire (LNOS) low-loss acoustic delay line (ADL). The thin-film LN/SiO2 bilayer acoustic waveguide, together with the single-phase unidirectional transducer (SPUDT) design, is key to attaining low insertion loss (IL) […]

Phase-change nanodroplets (PCNDs) are customizable and controllable theranostic agents of particular interest in extravascular therapies such as drug delivery and histotripsy. High-bulk-boiling-point (HBP) PCNDs are preferred for their enhanced thermal stability under physiological temperature to achieve on-demand therapeutic effects on target sites—mainly in tumor tissue. However, the […]

Focused ultrasound (FUS) and microbubbles facilitate blood-brain barrier opening (BBBO) noninvasively, transiently, and safely for targeted drug delivery. Unlike state-of-the-art approaches, in this study, we demonstrate for the first time the simultaneous, bilateral BBBO in non-human primates (NHPs) using acoustic holograms at caudate and putamen structures. The simple and low-cost system with a […]